Coronary Disease

Article

First-in-Human Gene Therapy for Vein Graft Failure

May 28, 2026 | Nawwar Al Attar

Background and Rationale Coronary artery bypass graft (CABG) surgery remains a cornerstone treatment for advanced coronary heart disease. However, the long-term efficacy of CABG is frequently compromised by the failure of saphenous vein grafts (SVGs)....

JANS Article

In Vivo Base Editing of PCSK9 With VERVE-102 for Hypercholesterolemia

June 25, 2026 | Vincent SierSilver Contributor

In this article, the authors report interim results of Heart 2, a phase 1, open label, single ascending dose study of VERVE 102, a GalNAc lipid nanoparticle delivering mRNA for...

Event

The Houston Aortic Symposium 2027

March 4, 2027

Thursday, March 4, 2027 – Saturday, March 6, 2027 @ 8:00 am – 12:00 pm – The Houston Aortic Symposium brings together world-renowned cardiothoracic and vascular surgeons to deliver cutting-edge...

JANS Article

Time of Day of Cardiac Surgery and Postoperative Outcomes in the UK: A Secondary Analysis of Linked National Datasets

June 11, 2026 | Joel DunningGold ContributorSilver Commentor

This article examines the impact of surgery timing on postoperative outcomes in cardiac surgery. An analysis of data from 24,068 patients revealed that surgeries performed in the late morning (10:00...

Article

First-in-Human Gene Therapy for Vein Graft Failure

May 28, 2026 | Nawwar Al Attar

Background and Rationale Coronary artery bypass graft (CABG) surgery remains a cornerstone treatment for advanced coronary heart disease. However, the long-term efficacy of CABG is frequently compromised by the failure...

JANS Article

Coronary Plaque Sampling Reveals Molecular Insights Into Coronary Artery Disease

August 7, 2023 | Aristotle ProtopapasGold Commentor

In a research letter on a small pilot genomic study of sampling coronary atheroma, the authors offer a brief explanation on how their technique can be applied to detect stability...

JANS Article

2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines

July 27, 2023 | Cameron LindSilver Contributor

These new guidelines contain wide-ranging recommendations on the use of beta-blockers, sodium-glucose cotransporter-2 (SGLT2) inhibitors and glucagon-like peptide-1, and other medical therapies to treat chronic coronary disease. They also contain...

Video

Patch Augmentation of Anomalous Left Main Coronary Artery from Right Coronary Sinus

June 27, 2023 | Anibal Ibanez…

The Patient The patient is a fifty-three-year-old male with medical history notable for neuroendocrine tumor, which was treated with a pylorus-preserving pancreaticoduodenectomy. The patient was symptomatic and complained of shortness...

Video

Postinfarction Ventricular Septal Defect Closure Without Ventriculotomy—A Novel Method

June 6, 2023 | Mario Torre…

Postinfarction ventricular septal defect is a rare complication of myocardial infarction with a high mortality rate (1). Standard repair techniques—infarcectomy and infarct exclusion—are performed through a left ventriculotomy. These methods...

Video

Internal Mammary Artery Harvest: Two Techniques with Tips and Tricks

May 30, 2023 | Stephen Spindel…

This video describes the pedicle and skeletonization techniques for internal mammary artery harvest. Tips and tricks are discussed, as well as how to increase mammary length. Disclaimer The information and...

Video

How to Deal with a “Seagull Deformity” in Diamond-Shaped Sequential Coronary Anastomoses

March 20, 2023 | Vasily Kaleda…

One of the most frequent and feared complications of sequential diamond-shaped coronary anastomoses is the so-called seagull deformity, which causes a turbulence flow within the graft and the risk of...

JANS Article

Adjunctive Radial Artery Grafts No Better Than SVGs in Multivessel CABG

October 13, 2022 | Cameron LindSilver Contributor

The CSP 474 trial challenges some of the conventional knowledge around graft choice in CABG surgery, as was presented at the European Association for Cardiothoracic Surgery (EACTS) conference. The trial...

JANS Article

Dual Therapy Offers Both Benefit and Risk After Common Type of Cardiac

August 19, 2022 | Mary Hammon

A new analysis by a team led by Dr. Mario Gaudino of Weill Cornell Medicine and NewYork-Presbyterian shows that a combination of two antiplatelets drugs can benefit patients after coronary...

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