Coronary Disease

JANS Article

Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting for Unprotected Left Main Stenosis: 10-Year Final Results From the Randomised, Open-Label, Non-Inferiority NOBLE Trial

May 13, 2026 | Vincent SierSilver Contributor

In this article, the authors report the 10-year final results of the NOBLE trial comparing percutaneous coronary intervention (PCI) with newer generation drug–eluting stents vs coronary artery bypass grafting (CABG) for unprotected left main coronary...

JANS Article

In Vivo Base Editing of PCSK9 With VERVE-102 for Hypercholesterolemia

June 25, 2026 | Vincent SierSilver Contributor

In this article, the authors report interim results of Heart 2, a phase 1, open label, single ascending dose study of VERVE 102, a GalNAc lipid nanoparticle delivering mRNA for...

Event

The Houston Aortic Symposium 2027

March 4, 2027

Thursday, March 4, 2027 – Saturday, March 6, 2027 @ 8:00 am – 12:00 pm – The Houston Aortic Symposium brings together world-renowned cardiothoracic and vascular surgeons to deliver cutting-edge...

JANS Article

Time of Day of Cardiac Surgery and Postoperative Outcomes in the UK: A Secondary Analysis of Linked National Datasets

June 11, 2026 | Joel DunningGold ContributorSilver Commentor

This article examines the impact of surgery timing on postoperative outcomes in cardiac surgery. An analysis of data from 24,068 patients revealed that surgeries performed in the late morning (10:00...

Article

First-in-Human Gene Therapy for Vein Graft Failure

May 28, 2026 | Nawwar Al Attar

Background and Rationale Coronary artery bypass graft (CABG) surgery remains a cornerstone treatment for advanced coronary heart disease. However, the long-term efficacy of CABG is frequently compromised by the failure...

JANS Article

Overall and Cause-Specific Mortality in Randomized Clinical Trials Comparing Percutaneous Interventions With Coronary Bypass Surgery: A Meta-Analysis

October 26, 2020 | Aristotle ProtopapasGold Commentor

Within the limitations of a meta-analysis, a useful work advancing that PCI may have a hitherto masked or hidden mortality

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JANS Article

Implications of Alternative Definitions of Peri-Procedural Myocardial Infarction After Coronary Revascularization

October 12, 2020 | Aristotle ProtopapasGold Commentor

An analysis, from the cardiology viewpoint, of the MI nomenclature issues around the external validity of the EXCEL trial that undermined the EACTS support of the relevant 2018 guidelines

...
JANS Article

Place and Causes of Acute Cardiovascular Mortality During the COVID-19 Pandemic

October 4, 2020 | Aristotle ProtopapasGold Commentor

The authors are concerned about the ‘deaths at home’ having the greatest contribution to the excess of acute cardiovascular deaths in that period of the recent epidemic, AND LOCKDOWN in...

JANS Article

A Novel Technique of Endoscopic Vein Harvesting With Preserved Perivascular Tissue

September 21, 2020 | Jessica Luc

In this article, the authors present a novel no-touch saphenous vein harvesting technique with preservation of the perivascular tissue with use of the harvester (MAQUET Getinge Group, Getinge AB, Göteborg,...

JANS Article

Dual Antiplatelet Therapy After Percutaneous Coronary Intervention and Drug-Eluting Stents: A Systematic Review and Network Meta-Analysis

September 15, 2020 | Aristotle ProtopapasGold Commentor

An open-access large metanalysis on the utility and risks of antiplatelets after PCI. Of note, mortality was not a primary endpoint. The message is that long dual antiplatelet use is...

JANS Article

Obesity Phenotypes, Diabetes, and Cardiovascular Diseases

May 23, 2020 | Aristotle ProtopapasGold Commentor

a readable review that advances the position that Adolphe Quetelet’s formula is now clinically obsolete

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JANS Article

Safe Reintroduction of Cardiovascular Services During the COVID-19 Pandemic: Guidance From North American Society Leadership

May 6, 2020 | Jessica Luc

This article describes recommendations from the North American leadership in regards to the safe reintroduction of cardiovascular services during the COVID-19 pandemic including, but not limited to, ethical considerations, the...

JANS Article

Empty Non-Coronavirus Beds Raise Fears That Sickest Are Avoiding NHS

April 13, 2020 | Aristotle ProtopapasGold Commentor

Topical review on the epidemic in Britain, with a number of observations that relate to the cardiothoracic surgeons and all healthcare professionals: -The assertion that the National Health Service in...

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