Coronary Disease

JANS Article

Heart Surgeons Perform World’s First Combined Robotic AVR and CABG

December 19, 2024 | Joel DunningGold ContributorSilver Commentor

Surgeons at the West Virginia University Heart and Vascular Institute performed the world’s first combined robotic aortic valve replacement (AVR) and coronary artery bypass grafting (CABG) through a single small incision. The groundbreaking procedure, led...

JANS Article

In Vivo Base Editing of PCSK9 With VERVE-102 for Hypercholesterolemia

June 25, 2026 | Vincent SierSilver Contributor

In this article, the authors report interim results of Heart 2, a phase 1, open label, single ascending dose study of VERVE 102, a GalNAc lipid nanoparticle delivering mRNA for...

Event

The Houston Aortic Symposium 2027

March 4, 2027

Thursday, March 4, 2027 – Saturday, March 6, 2027 @ 8:00 am – 12:00 pm – The Houston Aortic Symposium brings together world-renowned cardiothoracic and vascular surgeons to deliver cutting-edge...

JANS Article

Time of Day of Cardiac Surgery and Postoperative Outcomes in the UK: A Secondary Analysis of Linked National Datasets

June 11, 2026 | Joel DunningGold ContributorSilver Commentor

This article examines the impact of surgery timing on postoperative outcomes in cardiac surgery. An analysis of data from 24,068 patients revealed that surgeries performed in the late morning (10:00...

Article

First-in-Human Gene Therapy for Vein Graft Failure

May 28, 2026 | Nawwar Al Attar

Background and Rationale Coronary artery bypass graft (CABG) surgery remains a cornerstone treatment for advanced coronary heart disease. However, the long-term efficacy of CABG is frequently compromised by the failure...

JANS Article

Individualizing Revascularization Strategy for Diabetic Patients With Multivessel Coronary Disease

October 18, 2019 | Mark FergusonBronze Contributor

Using data from the FREEDOM (Future Revascularizaiton Evaluation in Patients with Diabetes Mellitus: Optimal Management of Multivessel Disease) trial, the authors developed an 8 variable model that predicts individual risk...

JANS Article

The Gender Gap in ACS: Sex-Specific Thresholds of High-Sensitivity Troponin in Patients With Suspected Acute Coronary Syndrome

October 15, 2019 | Mark FergusonBronze Contributor

Using gender specific thresholds for abnormalities in cardiac troponin I, the rate of injury among women increased by 42%. This did not translate into improved management of women, who remained...

JANS Article

Antithrombotic Treatment After Coronary Artery Bypass Graft Surgery: Systematic Review and Network Meta-Analysis

October 11, 2019 | Benjamin Bidstrup

This timely review examines the use of single and mutiple agents to decrease saphenous graft failure after CABG. These are difficult and expensive studies to perform, requiring repeat imaging after...

JANS Article

Skeletonisation Contributing to a Reduction of Sternal Wound Complications: a Retrospective Study in OPCAB Patients

September 18, 2019 | Edward Savage

This is a retrospective study in OPCAB patients comparing patients who received skeletonized versus nonskeletonized SIMA and BIMA grafts. They reported patients with any sternal wound complication including redness or...

JANS Article

CABG Improves Outcomes in Patients With Ischemic Cardiomyopathy: 10-Year Follow-Up of the STICH Trial

September 14, 2019 | Edward Savage

This study reports ten year outcomes of the STICH trial. Comparing CABG to medical therapy groups, the authors note that CABG reduced all cause, cardiovascular, and heart failure hospitalizations. This...

JANS Article

Most Promising’ Cardioprotective Strategy Ends Up a Bust

September 3, 2019 | Mark FergusonBronze Contributor

Remote ischemic preconditioning did not influence 12-month survival or readmission rates in a randomized trial involving more than 5,400 patients undergoing percutaneous coronary intervention after ST-segment elevation MI.

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JANS Article

A More COMPLETE Picture of Revascularization in STEMI

September 1, 2019 | Aristotle ProtopapasGold Commentor

Interesting viewpoint of a cardiologist on low-SYNTAX subjects.

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JANS Article

Effects of Intracoronary Nicorandil on Myocardial Microcirculation and Clinical Outcomes in Patients With Acute Myocardial Infarction: A Meta-Analysis of Randomized Controlled Trials

August 29, 2019 | Aristotle ProtopapasGold Commentor

An interesting meta-analysis discouraging perhaps the use of this KATP modulator, especially after surgical revascularization where optimization of serum potassium is generally sought.

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