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Esophageal Cancer - Multimodality Therapy
To understand the shift toward nonsurgical management of esophageal cancer, researchers set out to determine the long-term quality of life (QOL) after esophagectomy. This study found that, in esophagectomy patients surviving more than three years,...
Although the standard of care in the West for regionally advanced esophageal cancer entails induction therapy, this is routinely not the case in China. This randomized trial involving over 450...
In this multiinstitutional retrospective study, administration of adjuvant chemotherapy for patients with persistent nodal disease after induction therapy and esophagectomy was associated with improved survival.
...Stiles and colleagues evaluated outcomes for patients with esophageal cancer undergoing surgical resection after either neoadjuvant chemoradiation or preoperative chemotherapy without radiation. The authors evaluated disease-free and cancer-specific survival from...
This retrospective analysis of salvage esophagectomy after definitive chemoradiotherapy in 308 patients identified increased mortality and morbidity associated with squamous histology and radiation dose >55 Gy. Survival at three years...