Molecular Biology
High tumor mutational burden (TMB) predicts not only response to immune checkpoint inhibitors (ICI) in advanced non-small cell lung cancer (NSCLC) but also immune-related toxicity. In this single-center cohort of 1,215 patients treated with ICI...
High tumor mutational burden (TMB) predicts not only response to immune checkpoint inhibitors (ICI) in advanced non-small cell lung cancer (NSCLC) but also immune-related toxicity. In this single-center cohort of...
An experiment that may find some translational value in the drive to elucidate inflammation as a target for controlling cardiovascular disease. Columbia University has on this occasion focused on elucidating...
This paper details an under-development animal model to study the vascular pathology of vein grafts in a variation of the initial Carrel canine bypass experiment. The possible findings on detrimental...
The clinical problem addressed in this study is bleeding in patients who undergo ECMO. The authors endeavor to address the issue through a quantitative cohort study by reflecting on how...
A paper that addresses a gap in knowledge and will guide future research: of particular interest, the penultimate paragraph on The Role of Interventions.
...Interesting study of hypertrophied human cardiomyocytes
...Interesting early work on the prognostic value in aortic disease of the cross-link component in the elastin.
...An extremely useful and free-access update on a major vascular entity. The ‘Areas of Uncertainty’ is a particularly useful chapter, discussing the available technology and its current supra-renal limitations and...
An authoritative, scholarly but very readable review of the evolution of mechanical circulatory support of the left ventricle from the non-surgical standpoint.
...A brief editorial with a clear message on the importance of genomics in tailoring aortic surgery to individual patients’ long-term outlook.in bicuspid aortic valve disease in the absence of arch...
An editorial that may herald the decrease in aspirinization and the rise of ticagrelor monotherapy in Percutaneous stenting of coronary arteries. There might be a peripheral relevance to the group...
A scholarly and sober narrative review on , as the authors state, a ‘ hot topic’ that is already being debated in Multidisciplinary Meetings and Lung Cnacer Boards.
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