This paper details an under-development animal model to study the vascular pathology of vein grafts in a variation of the initial Carrel canine bypass experiment. The possible findings on detrimental effects of hydrostatic distention, if and when quantified, may alter surgeons’ harvesting techniques.
Early Injury Landscape in Vein Harvest by Single-Cell and Spatial Transcriptomics
Submitted by: Aristotle Protopapas
Source: Circulation Research
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Author(s): Marina E. Michaud, Lucas Mota, Mojtaba Bakhtiari, Beena E. Thomas, John Tomeo, William Pilcher, Mauricio Contreras, Christiane Ferran, Swati Bhasin, Leena Pradhan-Nabzdyk, Frank W. LoGerfo, Patric Liang and Manoj K. Bhasin
