Transplantation - Heart

JANS Article

Gene-Edited Pig Cardiac Xenotransplantation as a Bridge to Allotransplantation in Infants: Progress in a Pig-to-Baboon Model

July 9, 2026 | Ali MashadiSilver Contributor

Cleveland and colleagues present a translational study evaluating porcine cardiac xenotransplantation as a potential bridge to allotransplantation in infants with congenital heart disease. A total of 15 baboons underwent implantation of gene-edited porcine cardiac xenografts....

JANS Article

Gene-Edited Pig Cardiac Xenotransplantation as a Bridge to Allotransplantation in Infants: Progress in a Pig-to-Baboon Model

July 9, 2026 | Ali MashadiSilver Contributor

Cleveland and colleagues present a translational study evaluating porcine cardiac xenotransplantation as a potential bridge to allotransplantation in infants with congenital heart disease. A total of 15 baboons underwent implantation...

Video

Robotic MVR, MAZE Procedure, and Appendage Ligation at King Faisal Hospital

July 1, 2026 | Joel DunningGold ContributorSilver Commentor…

This video series showcases a robotic mitral valve replacement performed by Dr. Feras Khaliel, a world leader in robotics, at King Faisal Specialist Hospital, Riyadh, Saudi Arabia. CTSNet Editor-in-Chief Joel...

Video

SCTS 2026 | Mesenchymal Stem Cells and Transplants

June 12, 2026 | Laurens Ceulemans…

At the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting, leading surgeons presented on mesenchymal stem cells and transplants. Dr. Laurens Ceulemans, a thoracic and transplant surgeon...

Podcast

The Beat With Joel Dunning Ep. 160: Shifting Healthcare Policy in Surgery

June 11, 2026 | Joel DunningGold ContributorSilver Commentor…

This week on The Beat, CTSNet Editor-in-Chief Joel Dunning spoke with Dr. Nikki Stamp, a cardiothoracic surgeon at Mount Private Hospital in Perth, Western Australia, who also serves as an...

JANS Article

Transplantation of a Genetically Modified Porcine Heart Into a Live Human

February 27, 2025 | Akshay PatelSilver Contributor

This article presents findings from the second-ever pig-to-human heart xenotransplant. A 58-year-old patient with end-stage heart failure received a 10-gene-edited porcine heart and was maintained on a novel anti-CD40L immunosuppressive...

JANS Article

Engineered Heart Muscle Allografts for Heart Repair in Primates and Humans

February 13, 2025 | Mateo Marin-Cuartas

Researchers have shown that patches of muscle grown from stem cells can help repair a failing heart. A laboratory-grown biological transplant with the potential to stabilize and strengthen the heart...

JANS Article

Transcatheter Valve Replacement in Severe Tricuspid Regurgitation

December 12, 2024 | Mateo Marin-Cuartas

In the TRISCEND II trial, a total of 400 patients with severe symptomatic tricuspid regurgitation were randomized in a 2:1 ratio to undergo either transcatheter tricuspid valve replacement with medical...

Video

How I Do It: Pediatric Orthotopic Heart Transplant

June 25, 2024 | Alan ODonnellBronze Contributor…

In this video, the patient is a six-month-old, 6.4 kg infant with a new diagnosis of dilated cardiomyopathy. The patient was at home and presented at the hospital in extremis....

JANS Article

Current Status of Cardiac Xenotransplantation: Report of a Workshop of the German Heart Transplant Centers

June 5, 2024 | Jessica Bogensberger

This report comprises the contents of the presentations and following discussions of a workshop of the German Heart Transplant Centers in Martinsried, Germany on cardiac xenotransplantation. Summary: This report comprises...

JANS Article

Woman Becomes First Patient to Undergo Combined Heart Pump Implant and Pig Kidney Transplant

May 2, 2024 | Cameron LindSilver Contributor

A fifty-four-year-old woman became the first person to simultaneously receive a gene-edited pig kidney transplant and mechanical heart valve implantation. Surgeons performed the heart pump procedure first before performing the...

Article

Facing the Challenges of Heart and Lung Harvesting and Procurement in Resource Limited Settings: Colombia

April 25, 2024 | Eric Vinck…

Background The first heart transplant in Colombia was performed in Medellín on December 1, 1985 and the first successful lung transplant in Colombia was performed on October 28, 1997 at...

JANS Article

Trends and Outcomes of Heart Transplantation in Adults With Congenital Heart Disease

April 24, 2024 | EACTS StaffSilver Contributor

Heart transplantation for adult congenital heart disease (ACHD) is associated with challenging pretransplant support, long waitlists, and high early post-transplant mortality. The authors used 2,737 patients from the United Network...

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