Assessing Donor-Recipient Size Mismatch in Pediatric Heart Transplantation: Lessons Learned from Over 7,500 Transplants

This study determined which measurement—height, weight, BMI, BSA, predicted heart mass, total cardiac volume (TCV)—is most important for assessing donor-recipient heart size mismatch. Amdani and colleagues investigated the Pediatric Heart Transplant Society Database to address this question and identify the effects of donor-recipient size mismatch using a range of parameters. Outcomes were assessed at one and five years of follow up. Interestingly, they report that height and TCV are more relevant to long-term risk of graft loss compared to other metrics.