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Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China

Thursday, March 26, 2020

Submitted by

Mark Ferguson

Source

Source Name: JAMA Cardiology

Source URL: https://jamanetwork.com/journals/jamacardiology/fullarticle/2763524

Author(s)

Shaobo Shi, Mu Qin, Bo Shen, Yuli Cai, Tao Liu, Fan Yang, Wei Gong, Xu Liu, Jinjun Liang, Qinyan Zhao, He Huang, Bo Yang, Congxin Huang

In a cohort of 416 patients hospitalized with COVID-19, nearly 20% had elevated troponins indicating myocardial injury. These patients also had a host of other serum and radiographic abnormalities, were older, had more comorbidities, and more often required ventilatory support. Their mortality rate was 51% compared to 4.5% for other hospitalized patients. Elevated troponins were an independent predictor of mortality (HR 4.26).