This study compared vein bypass with best endovascular treatment for chronic limb-threatening ischemia. The twice-quoted phrase of the RCT manuscript: “Participants were excluded if they had ischemic pain or tissue loss considered not to be primarily due to atherosclerotic peripheral artery disease” needs further clarification. Major amputation or death occurred in 63 percent of patients in the vein bypass group and 53 percent of patients in the best endovascular treatment group. Researchers concluded that for this group, a revascularization procedure to restore limb perfusion should be considered.
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BASIL-2 Trial: A Vein Bypass First Versus a Best Endovascular Treatment First Revascularisation Strategy for Patients with Chronic Limb Threatening Ischemia Who Required an Infrapopliteal
Submitted by: Aristotle Protopapas
Source: The Lancet
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Author(s): Prof Andrew W Bradbury, Catherine A Moakes, Matthew Popplewell, Lewis Meecham, Gareth R Bate, Lisa Kelly, Ian Chetter, Athanasios Diamantopoulos, Arul Ganeshan, Jack Hall, Simon Hobbs, Prof Kim Houlind, Hugh Jarrett, Suzanne Lockyer, Jonas Malmstedt, Jai V Patel, Smitaa Patel, S Tawqeer Rashid, Athanasios Saratzis, Gemma Slinn, Prof D Julian A Scott, Hany Zayed, Prof Jonathan J Deeks
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