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  1. Cardiac

Beating-Heart Transplantation After Thoracoabdominal Normothermic Regional Perfusion in Controlled DCD Donors

  • October 29, 2026

Submitted by: Shrikar Modukuri

Source: Journal of Heart and Lung Transplantation
Source URL: https://www.jhltonline.org/article/S1053-2498(26)02085-1/abstract

Keywords:

  • Mechanical Support & Transplant
Author(s): Matteo Marro, Andrea Lechiancole, Erika Simonato, Giulia Agostini, Serena Franchetti, Laura Anna Stella, Antonio Loforte, Michele William La Torre, Mauro Rinaldi, Massimo Boffini, Igor Vendramin

In this two-center Italian case series of six beating-heart transplants from controlled donation after circulatory death (DCD) donors, thoracoabdominal normothermic regional perfusion restored satisfactory biventricular function and enabled in situ graft assessment. Furthermore, beating-heart procurement and implantation under continuous normothermic coronary perfusion yielding 100 percent 30-day patient and graft survival, no severe primary graft dysfunction, and preserved biventricular function at discharge, supporting further evaluation of this ischemia-sparing strategy in larger studies.

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TAGS
  • Cardiac Guidelines
  • Heart Failure - Ischemic
  • Transplantation - Heart

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