Changes in Risk Profile Over Time in the Population of a Pediatric Heart Transplant Program

Changes in risk profile and outcomes over 40 years were assessed from the Stanford experience with heart transplant in children.  Age at transplant decreased in the most recent time period from about 10 to 5.6 years.  The use of mechnical support as bridge increased dramatically over the time of the study.  Long-term survival increased dramatically, and patients with cardiomyopathy had a survival advantage over those with congenital heart disease.