Consideration of a New Definition of Clinically Relevant Myocardial Infarction After Coronary Revascularization: An Expert Consensus

Submitted by: Erica CurcioGold Contributor

Source: Journal of the American College of Cardiology

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Author(s): Moussa ID, Klein LW, Shah B, Mehran R, Mack MJ, Brilakis ES, Reilly JP, Zoghbi G, Holper E, Stone GW.

This paper is an expert consensus on the new definition of relevant myocardial infarction following both PCI and CABG. In patients with normal baseline CK-MB, post-procedural MI is defined as a peak CK-MB rise, measured within 48 hours of the procedure, equal or greater  than 10-times the local laboratory upper limit of normal (ULN) or equal or greater than 5-times the local laboratory ULN with new pathologic Q-waves in more than 2 contiguous leads or new persistent LBBB, OR in the absence of CK-MB measurements and a normal baseline cTn, a cTn (I or T) level  rise, measured within 48 hours of the procedure, greater than 70-times the local laboratory ULN, or greater than 35-times the ULN with new pathologic Q-waves in more than 2 contiguous leads or new persistent LBBB.  

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