Deep hypothermic circulatory arrest during the arterial switch operation is associated with reduction in cerebral oxygen extraction but no increase in white matter injury

Submitted by: Erica CurcioGold Contributor

Source: Journal of Thoracic and Cardiovascular Surgery

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Author(s): PP Drury, AJ Gunn, L Bennet, A Ganeshalingham, K Finucane, D Buckley, J Beca

This study compared short periods of deep hypothermic arrest to bypass alone in 18 infants undergoing arterial switch to assess neurophysiologic outcomes and white matter injury.  Deep hypothermic arrest was associated with reduced oxygen extraction and transient EEG suppression but there was no difference between the groups in white matter injury.     

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