Percutaneous edge to edge repair with MitraClip is typically used in situations of central mitral insufficiency (MI). In this study, the authors evaluate the applicability of this technique in non-central MI. They have carried out a retrospective analysis of their own results in a group of 79 patients. Although patients with non-central MI had higher pulmonary pressures and wider basal vena contracta, there were no significant differences in procedural success or complications. In addition, there were no significant differences in all-cause mortality, readmission for heart failure, residual MI and NYHA status at 1 and 6 months. Although the study is probably too small in size as to provide strong evidence, the results suggest that non-central MI could be amenable to treatment with percutaneous edge to edge repair techniques.
Echocardiographic and Clinical Outcomes of Central Versus Noncentral Percutaneous Edge-to-Edge Repair of Degenerative Mitral Regurgitation
Submitted by: Erica Curcio
Source: Journal of the American College of Cardiology
Source URL: http://www.ncbi.nlm.nih.gov/pubmed/24013059
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Author(s): Estévez-Loureiro R, Franzen O, Winter R, Sondergaard L, Jacobsen P, Cheung G, Moat N, Ihlemann N, Ghione M, Price S, Duncan A,Rosenberg TS, Barker S, Di Mario C, Settergren M.