The first tissue-engineered airway transplantation: 5-year follow-up results

Submitted by: Erica CurcioGold Contributor

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Author(s): A Gponfiotti, MO Jaus, D Barale, S Baiguera, S Comin, F Lavorini, G Fontana, O Sibila, G Rombola, P Jungebluth, P Macchiarini

This 5-year follow-up of the first tissue engineered airway using decellularized human trachea demonstrated that the graft became well vascularized, had normal ciliary function and mucous clearance, and maintained a normal diameter. no anti-donor antibodies developed. The graft replaced the left main bronchus that was affected by tracheomalacia. The proximal anastomosis developed stenosis requiring stenting.

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