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The German Registry of Acute Aortic Dissection Type A Score for 30-Day Mortality Prediction in Type A Acute Aortic Dissection Surgery: A Systematic Review and Meta-Analysis

Thursday, July 24, 2025

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Source

Source Name: European Journal of Cardio-Thoracic Surgery

Author(s)

Marco Gemelli, Thanakorn Rojanathagoon, Jef van den Eynde, Enrico G Italiano, Tea Lena, Michel Pompeu Sá, Vito D Bruno, Manraj Sandhu, Robert Pruna-Guillen, Aung Y Oo, Martin Czerny, Michele Gallo, Mark S Slaughter, Vincenzo Tarzia, Eltayeb Mohamed Ahmed, Cha Rajakaruna, Gino Gerosa

This meta-analysis evaluated the performance of The German Registry of Acute Aortic Dissection Type A (GERAADA) score in predicting 30-day mortality after type A acute aortic dissection (TAAAD) surgery across 11 studies. With an observed mortality of 12.2 percent, GERAADA showed moderate discrimination (AUC 0.70) and good calibration, with a pooled expected mortality of 18.4 percent compared to EuroSCORE II's 5.8 percent. When both scores were directly compared in five studies, GERAADA showed better calibration than EuroSCORE II, while the discrimination between the two remained similar. The study concludes GERAADA offers better calibration for predicting 30-day postoperative mortality following TAAAD and highlights the challenges of predicting outcomes in complex cases. 

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