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Lymphovascular Invasion as a Prognostic Indicator in Stage I Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis

  • March 2, 2014

Submitted by: Mark FergusonBronze Contributor

Source: Annals of Thoracic Surgery
Source URL: http://www.annalsthoracicsurgery.org/article/S0003-4975%2813%2902491-0/abstract

Keywords:

Author(s): Nathan M. Mollberg, Carrie Bennette, Eric Howell, Leah Backhus, Beth Devine, Mark K. Ferguson

LVI is thought to be an adverse prognostic indicator of survival in patients with NSCLC. This review quantified the relationship of LVI and survival. The unadjusted effect of LVI for recurrence-free survival was HR=3.63 and for overall survival was HR=2.38. After adjustment for covarates, these HRs were 2.52 and 1.81, both highly significant.

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