This meta-analysis evaluated results from 6 studies totalling 868 patients randomized to local control (radiotherapy vs surgery) after induction therapy for NSCLC with N2 disease. Four studies evaluated induction chemotherapy, the other 2 evaluated induction chemoradiotherapy. Differences in outcomes were not significant, but there was a strong trend favoring surgery as part of multimodality therapy for NSCLC with N2 disease.
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Outcome of surgery versus radiotherapy after induction treatment in patients with N2 disease: systematic review and meta-analysis of randomised trials
Submitted by: Mark Ferguson
Source: Thorax
Source URL: http://thorax.bmj.com/content/70/8/764?etoc
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Author(s): PJ McElnay, A Choong, E Jordan, F Song, E Lim
