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Outcomes of No-Touch Vs Conventionally Harvested Saphenous Veins for Coronary Artery Bypass Surgery: A Meta-Analysis of Randomized Trials

Thursday, December 4, 2025

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Source

Source Name: European Journal of Cardio-Thoracic Surgery

Author(s)

Sigrid Sandner, Aina Hirofuji, Polina Mantaj, Antonino Di Franco, Mohamed Rahouma, Alexander Gregg, Katherine Krieger, Michelle Demetres, Mario Gaudino

This meta-analysis of eight randomized clinical trials (RCT) compared no-touch (NT) vs conventional (CON) saphenous vein (SV) harvesting in coronary bypass surgery. At a 3.7-year follow-up, NT-SV harvesting showed significantly lower graft failure rates compared to CON-SV. However, mortality and major adverse cardiac events were similar between groups. NT-SV harvesting was associated with higher leg wound complications. The author’s conclusion was that NT-SV harvesting reduces graft failure but increases wound complications; thus, strategies to mitigate harvest-site complications are needed. 

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