welcomes you to the new, improved website!The CROSS trials randomized pts with esophageal cancer or GEJ cancer to surgery vs induction chemoradiotherapy (CRT) followed by surgery. Prior studies reported a significant improvement in survival and freedom from recurrence associated with induction therapy. In this report, CRT reduced locoregional recurrence from 34% to 14% and reduced peritoneal carcinomatosis from 14% to 4%. Local recurrence within the RT field occurred in only 5% of patients.
Patterns of Recurrence After Surgery Alone Versus Preoperative Chemoradiotherapy and Surgery in the CROSS Trials
Submitted by: Mark Ferguson
Source: Journal of Clinical Oncology
Keywords:
Author(s): V Oppedijk, A van der Gaast, JJB van Lanschot, P van Hagen, R van Os, CM van Rij, MJ van der Sangen, JC Beukema, H Rutten, PH Spruit, JG Reinders, DJ Richel, MI van Berge Henegouwen, MCCM Hulshof