welcomes you to the new, improved website!The effectivity of Sildenafil for preoperative preconditioning in pediatric heart surgery was tested in a randomized trial. Thirteen children each with low-dose (0.06 mg/kg), high-dose (0.6 mg/kg) or no preconditioning underwent VSD closure. Sildenafil application did not alter myocardial injury, cardiac function, inotropic needs or postoperative course.
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Preoperative Sildenafil administration in children undergoing cardiac surgery: a randomized controlled preconditioning study
Source: Eur J Cardiothorac Surg
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Author(s): Varsha Walavalkar, Egmond Evers, Suresh Pujar, Kiran Viralam, Shreesha Maiya, Stefan Frerich, Colin John, Shekhar Rao, Chinnaswamy Reddy, Bart Spronck, Frits W. Prinzen, Tammo Delhaas, and Ward Y. Vanagt
