Pro–surfactant protein B (pro-SFTPB) has been previously identified as a possible blood bio-marker for NSCLC. This study assessed whether it is an independent predictory of lung cancer development. Blood levels were measured in nearly 2500 individuals in a Candadian lung cancer screening study. The adjusted OR for pro-SFTPB was 2.22 and the area under the ROC curve (predictive accuracy) was 0.74.
Pro–Surfactant Protein B As a Biomarker for Lung Cancer Prediction
Submitted by: Erica Curcio
Source: Journal of Clinical Oncology
Keywords:
Author(s): DD Sin, M Tammemagi, S Lam, MJ Barnett, X Duan, A Tam, H Auman, Z Feng, GE Goodman, S Hanash, A Taguchi