Protamine Test Dose: Impact on Activated Clotting Time and Circuit Integrity

Submitted by: Christopher Anderson

Source: The Annals of Thoracic Surgery
Source URL: https://doi.org/10.1016/j.athoracsur.2021.04.059

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Author(s): Lauren Jansa, CPC, CCP Courtney Fischer, CPC, CCP Cyril Serrick, CPC, CCP Vivek Rao, MD, PhD

Recurrent observation of clot in the cardiopulmonary bypass circuit after the administration of a protamine test dose (PTD) prompted concern over the effects of PTDs on patient activated clotting times (ACTs).

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