Reactive thymic hyperplasia following chemotherapy for children with lymphoma: computed tomography may be able to provide valuable information to avoid over-treatment

Fifty-two children with thymic hyperplasia subsequent to chemotherapy for lymphoma were observed for a median of 33 months. Mediastinal masses were clear-shaped in 42 and diffuse in 10 children. Uptake of contrast agent was observed in all masses. Long-term regression of the hyperplasia was found in 42 and unchanged appearance in 10 children.