This single-center, real-world study compared a simplified, fluoroscopy-free mitral transcatheter edge-to-edge repair (M-TEER) workflow guided solely by transesophageal echocardiography (TEE) against the conventional approach using combined fluoroscopic and TEE guidance. Among 386 patients treated between 2021 and 2025 (286 sole-TEE, 100 combined), technical success was high in both groups (98.3 percent vs 97.0 percent) and 30-day major adverse events were low (2.8 percent vs7.0 percent), with no significant differences. Over a median follow-up of 16.5 months, the adjusted hazard ratios for cardiovascular mortality, all-cause mortality, and the composite of all-cause mortality with heart failure hospitalization were 1.52, 0.96, and 0.93, respectively; none reaching significance. M-TEER failure at one year was similar (4.8 percent vs 6.3 percent), and results held across propensity-matched and overlap-weighted sensitivity analyses. The authors conclude that sole-TEE-guided M-TEER is feasible with favorable outcomes in experienced centers.
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Real-World Outcomes After Simplified M-TEER Repair Under Sole TEE Guidance
Source: The Journal of Thoracic and Cardiovascular Surgery
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Author(s): Jianrui Ma, Chuangshi Wang, Xiaofang Yan, Peijian Wei, Jie Dong, Zizheng Liu, Jing Dong, Guangzhi Zhao, Fengwen Zhang, Fang Fang, Wenbin Ouyang, Shouzheng Wang, Fujian Duan, Yongquan Xie, Cheng Wang, Linlin Li, Xiangbin Pan
