Screening for Lung Cancer With Low-Dose Computed Tomography: A Systematic Review to Update the U.S. Preventive Services Task Force Recommendation

Submitted by: Erica CurcioGold Contributor

Source: Annals of Internal Medicine

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Author(s): Linda L. Humphrey; Mark Deffebach; Miranda Pappas; Christina Baumann; Kathryn Artis; Jennifer Priest Mitchell; Bernadette Zakher; Rongwei Fu; and Christopher G. Slatore

The USPST updated its review on lung cancer screening utilizing RTCs and cohort studies.  One trial reported that screening resulted in important reductions in cancer and all-cause mortality.  Three trials reported no benefit but were underpowered.  They conclude that screening offers benefit but is associated with potential harm that must be taken into consideration.

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