Sex Differences in Outcomes After Type A Acute Aortic Dissection

In this national registry analysis, the authors evaluated sex-related differences in outcomes among 2,857 patients undergoing surgical repair of type A acute aortic dissection in the United Kingdom between 1996 and 2019. The cohort included 1,907 men (67 percent) and 950 women (33 percent). Women were older and had a lower body mass index (BMI), whereas bicuspid aortic valve and aortic root aneurysm were more frequent among men. Operative strategies, including the rates of aortic root and total arch replacement, were comparable between the sexes. In-hospital mortality (18.7 percent vs 19.0 percent), cerebrovascular accident (12.5 percent vs 12.5 percent), dialysis (14.5 percent vs 14.6 percent), and median length of stay (13 vs 13 days) were similar in men and women. After inverse probability weighting, female sex was not independently associated with mortality or postoperative complications.