The Nationwide Inpatient Sample (NIS) was queried for aortic valve replacements conducted between 2003 and 2014. The data on a total of 166,809 patients (37% female) were analyzed with respect to outcomes in men vs. women. Hospital mortality was 40% higher in women than men (5.6% v. 4%, p
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Sex Differences in the Utilization and Outcomes of Surgical Aortic Valve Replacement for Severe Aortic Stenosis
Submitted by: Arie Blitz
Source: Journal of the American Heart Association
Source URL: http://jaha.ahajournals.org/content/6/9/e006370
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Author(s): Zakeih Chaker, Vinay Badhwar, Fahad Alqahtani, Sami Aljohani, Chad J. Zack, David R. Holmes, Charanjit S. Rihal, Mohamad Alkhouli

1 Comment
I expect correction of the dataset for size of the so called aortic ‘annulus’ to negate the gender bias, similarly to coronary size correction neutralises gender outcomes for CABG.
I am stunned that a paper accepted in JAHA got away with apparently NOT recording valve size (see Limitations) in such a context. Valve metrics are ultra-germane in risk profiling here, dear authors, and a retrospective review of aortic valve treatment should have these data available…. Nationwide Inpatient Sample is essentially a wrong tool to answer the research question, although gender comparison is always a catchy theme…