This propensity-matched study from the Montreal Heart Institute Ross Registry examined sex-based differences in outcomes following the Ross procedure. Among 816 adults undergoing full-root pulmonary autograft replacement (2011 to 2025), 512 were matched 2:1 (337 male, 175 female) on 24 preoperative variables. Early outcomes, 10-year survival (96.4 percent vs 92.9 percent), and reintervention (5.0 vs 2.7 percent) were similar. However, women had roughly a twofold higher progression of aortic regurgitation to grade 2 or greater (11.0 percent vs 20.5 percent at 10 years) and persistently worse New York Heart Association (NYHA) class, findings the authors frame as associations warranting sex-specific surveillance.
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The Ross Procedure: Determinants of Long-Term Durability
Submitted by: Shrikar Modukuri
Source: The Annals of Thoracic Surgery
Keywords:
Author(s): Nabil Ajmi, Arman Sarshoghi, Ismail Bouhout, Pierre-Emmanuel Noly, Nancy Poirier, Pierre-Luc Bernier, Walid Ben Ali, Ismail El-Hamamsy, Philippe Demers
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