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Valve-Sparing Aortic Root Replacement: Defining High-Volume Centres Using Prospective Data

  • June 25, 2026

Submitted by: Mujtaba MubashirGold Contributor

Source: European Journal of Cardio-Thoracic Surgery
Source URL: https://academic.oup.com/ejcts/article/68/6/ezag177/8691819

Keywords:

  • Aorta
Author(s): Pascal J. Govers, Michal J. Kawczynski, Samuel Heuts, Kevin M. Veen, Laurent de Kerchove, Emmanuel Lansac, Philippe Demers, Peter Verbrugghe, Igor Rudez, Aline Laubriet, Jan Vojacek, Elham Bidar, Johanna Takkenberg, Jolanda Kluin, Bardia Arabkhani, the Aortic Valve Research Network Investigators

This multicenter registry study evaluated the volume-outcome relationship in elective valve-sparing aortic root replacement (VSARR) to establish a threshold for high-volume centers. Utilizing prospective data from 2,668 patients across 37 centers within the Heart Valve Society Aortic Valve Database, the authors modeled early composite safety outcomes and long-term aortic valve reintervention-free survival. The authors found that annual institutional volume was not significantly associated with early postoperative composite complications (p=0.8); however, a significant nonlinear association emerged for long-term valve durability (p=0.002). Based on this, the authors identified an optimal threshold of greater than or equal to 12 cases per year for superior long-term survival and freedom from reintervention. Thus, while early safety endpoints remain uniformly low across centers due to low event rates, long-term valve durability relied heavily on ongoing institutional exposure. 

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