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George Krasopoulos, MD, PhD, MRCS,FRCS-CTh
BACKGROUND
Consultant in General Adult Cardiac Surgery, Oxford, UK (2013 – today)Hon. Professon in Cardiac Surgery, University of Cumbria, UK (2017-today)Hon. Senior Clinical Lecturer in Cardiac Surgery, University of Oxford (2015 – today)Specialist Lecturer in Cardiothoracic Surgery, University of Buckingham, UK (2015-today)Specialist Lecturer in Cardiothoracic Surgery, Anglia Ruskin Univeristy, UK (2016-today)Non-executive Director (Chair), Liga College, UK (2016-today)Consultant Adult Cardiac, Adult Structural & Adult Congenital Heart Disease, Thessaloniki, Greece (2010-2013)Consultant Adult Cardiac Surgeon, London, UK (2009-2010)Consultant Adult Cardiac Surgeon, Liverpool, UK (2008-2009)Senior Registrar in Cardiac Surgery, Royal Brompton & London Chest Hospitals, London, UK (2007-2008)Fellowship in Cardiovascular & Aortic Surgery, Toronto General Hospital, Toronto, Canada (2006-2007)Cardiothoracic Specialist Registrar (Adult & Paediatric), London, UK (2001 – 2006) Cardiothoracic Junior Residency, London, UK (1999 – 2000)Surgical Residence UK (1996 – 1999) & Greece (1994-1996)
OTHER INTERESTS
Minimally invasive cardiac surgeryAortic aneurysm surgeryAortic valve repairsAortic root repairsMitral valve repairsTricuspid valve repairsHeart valve replacementsCoronary artery by pass surgery (on pump & off pump)Ischaemic heart disease – LV reconstructionSurgery for atrial arrhythmiasTAVRSurgery for pericardial diseaseCoagulation & Platelet functionPulmonary embolismAdult congenital surgery
RESEARCH
Peer Review Journals
Influence of coronary territory on flow profiles of saphenous vein grafts
S Amin · RW Werner· PL Madsen · G Krasopoulos· DP Taggart
J. Cardiothoracic Surg. 2018 13:23 doi.org/10.1186/s13019-018-0709-6
· 1.413 Impact Factor
Effect of glycaemic control on complications following cardiac surgery: Literature review.
M. Navaratnarajah · R. Rea · R. Evans · F. Gibson · C. Antoniades · A. Keiralla · M. Demosthenous · G. Kassimis · G. Krasopoulos
J. Cardiothoracic Surg. 2018 13(1):10; doi 10.1186/s13019-018-0700-2
· 1.413 Impact Factor
Influence of external stenting on venous graft flow parameters in coronary artery bypass grafting: a randomized study
S Amin · RW Werner· PL Madsen · G Krasopoulos· DP Taggart
Intera. CardioVasc and Thor Surg 2018 1–6, doi:10.1093/icvts/ivy007
· 1.112 Impact Factor
Cardiac MRI T1-mapping Accurately Predicts Functional Recovery Post-Revascularization Without the Need for Gadolinium-based Contrast Agents
A Liu · RS Wijesurendra · J Liu · A Greiser · B Raman · M Petrou · G Krasopoulos· SK Piechnik· S Neubauer · VM Ferreira
Circulation 2018; (accepted for publication)
· 14.43 Impact Factor
Procedural and thirty-day outcomes following transferral implantation of the fully reposition able and retrievable Lotus valve without routine pre-dilatation in a consecutive patient chart: a single centre experience
N Ruparelia · K Thomas · JD Newton · K Grebenik · A Keiralla · G Krasopoulos· R Sayeed · AP Banning · RK Kharbanda.
Cardiovasc Revasc Med. 2017Nov; S1553-8389(17)30408-6. doi: 10.1016/j.carrev.2017.10.01
· 1.15 Impact Factor
Transfemoral Transcatheter Aortic Valve-in Valve Implantation for Aortic Valve Bioprosthesis Failure With the Fully Repositionableand Retrievable Lotus Valve: A Single-Center Experience.
N Ruparelia · K Thomas · JD Newton · K Grebenik · A Keiralla · G Krasopoulos· R Sayeed · AP Banning · RK Kharbanda.
J Invasive Cardiol. 2017 Sep;29(9):315-319. Epub 2017 Jul 15.
· 1.112 Impact Factor
Redox-sensitive regulation of cystine gamma-lyase (CSE) and the potential protective role of hydrogen sulfide (H2S) in the human heart.
A Tarum · C Psarros · F. Sanna · L. Herdman · I Akoumianakis · AS Antonopoulos · R Sayeed · G Krasopoulos· S Chuaiphichai · KM Channon · C Antoniades
European Heart Journal, 2017; 38, suppl_1, https://doi.org/10.1093/eurheartj/ehx493.P5388
· 15.203 Impact Factor
Echocardiographic pre-operative early mitral inflow velocity-toearly diastolic strain rate ratio predicts postoperative paroxysmal atrial fibrillation in patients undergoing CABG surgery.
G Sangha · EK Oikonomou · AS Antonopoulos · L. Herdman · R Sayeed · G Krasopoulos· M Petrou · KM Channon · C Antoniades
European Heart Journal, 2017; 38, suppl_1, https://doi.org/10.1093/eurheartj/ehx493.P5243
· 15.203 Impact Factor
False Positive Transit Time Flowmetry Graft Failure in Multivessel Coronary Spasm following Off-Pump Coronary Artery Bypass Grafting
G Kassimis · G Krasopoulos
Case Reports in Cardiology 2017; 3186047 DOI: 10.1155/2017/3186047
Detecting human coronary inflammation by imaging perivascular fat
S Antonopoulos · F Sanna · N Sabharwal · G Lazanos · EK Oikonomou · L Herdman · M Margaritis · C Shirodaria · AM Kampoli · I Akoumianakis · M Petrou · R Sayeed · G Krasopoulos· C Psarros · P Ciccone · CM Brophy · J Digby · A Kelion · R Uberoi · S Anthony · N Alexopoulos · D Tousoulis · S Achenbach · S Neubauer · KM Channon · C Antoniades
Science Translational Medicine Journal 2017; 9 (398) DOI: 10.1186/s12968-016-0318-
· 15.843 Impact Factor Media: The Guardian, NBC, FT, BBC News, US newspapers, French media
Predictive value of telomere length on outcome following acute myocardial infarction: Evidence for contrasting effects of vascular vs. blood oxidative stress
M Margaritis · F Sanna · G Lazanos · I Akoumianakis · S Patel · AS Antonopoulos · C Duke · L Herdman · C Psarros · EK Oikonomou · C Shinodata · M Petrou · R Sayeed · G Krasopoulos · R Lee · D Tousoulis · KM Channon · C Antoniades
European Heart Journal 2017 Apr 24. doi: 10.1093/eurheartj/ehx177
· 15.203 Impact Factor
A Prospective Study of External Stenting of Saphenous Vein Grafts to the Right Coronary Artery: The VEST II Study
DP Taggart · S Amin · J Djordjevic · EK Oikonomou · S Thomas · A-M Kampoli · N Sabharwal · C Antoniades · G Krasopoulos
Eur. J. Cardio-Thoracic Surg. 2017;51(5):952-958. doi: 10.1093/ejcts/ezw438.
· 2.81 Impact Factor
Splenic T1-mapping: a novel quantitative method for assessing adenosine stress adequacy on cardiovascular magnetic resonance imaging
A Liu · RS Wijesurendra · R Ariga· M Mahmod · E Levelt · A Greiser · M Petrou · G Krasopoulos· JC Forfar · RK Kharbanda· C Channon · S Neubauer· SK Piechnik · VM Ferreira
J. Cardiovasc. Mag. Reson. 2017 Jan 13;19(1):1. doi: 10.1186/s12968-016-0318-2.
· 5.75 Impact Factor
European real world trans-catheter aortic valve implantation: Systematic review and meta-analysis of European national registries
G Krasopoulos· F Falconieri· U Benedetto · J Newton · R Sayeed· RK Kharbanda · A Banning
J. Cardiothoracic Surg. (2016) 11:159. doi 10.1186/s13019-016-0
· 1.413 Impact Factor
Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase.
Reilly S · Liu X · Carnicer R · Recalde A · Muszkiewicz A · Jayaram R · Carena M · Wijesurendra R · Stefanini M · Surdo NC · Lomas O · Ratnatunga C · Sayeed R · Krasopoulos G · Rajakumar T · Bueno- Orovio A · Verheule S · Fulga T · Rodriguez B · Schotten U · Casadei B.
Science Translational Medicine May 2016; 8(340):340ra74-340ra74
• 15.84 Impact Factor
Mutual Regulation of Epicardial Adipose Tissue and Myocardial Redox State by PPAR- γ/Adiponectin Signaling
Antonopoulos AS · Margaritis M · Verheule S · Recalde A · Sanna F · Herdman L · Psarros C · Nasrallah H · Coutinho P · Akoumianakis I · Brewer AC · Sayeed R · Krasopoulos G · Petrou M · Tarun A · Tousoulis D · Shah AM · Casadei B · Channon KM · Antoniades C.
Circulation Research · 2016 Mar 4;118(5):842-55. doi: 10.1161
11.04 Impact Factor
Loss of Myocardial nNOS Mediated by Upregulation of miR-31 in Human Atria Contributes to Begetting of Atrial FibrillationX Liu · S Reilly · R Carnicer · A Recalde · A Muszkiewicz · R Jayaram · M C Carena · M Stefanini · R Wijesurendra · O Lomas · R Sayeed · G Krasopoulos · A Bueno-Orovio · B Rodriguez · B Casadei.
Biophysical Journal, February 2016; vol. 110, issue 3, p. 451a
• 3.972 Impact Factor
New Roles of the Interplay Between Endothelin and Insulin-like Growth Factor 1 in the Regulation of Vascular Redox State In Patients With Type 2 Diabetes and Coronary Atherosclerosis
I. Akoumianakis · M. Margaritis · F. Sanna · L. Herdman · C. Psarros · R. Sayeed · G. Krasopoulos · P. Wohlfart · K. Channon · C. Antoniades
Circulation 2015; 132, A18289
· 14.43 Impact Factor
Adiponectin as a Link Between Type 2 Diabetes and Vascular NADPH Oxidase Activity in the Human Arterial Wall: The Regulatory Role of Perivascular Adipose Tissue
A S Antonopoulos · M Margaritis · P Coutinho · C Shirodaria · C Psarros · L Herdman · F Sanna · R De Silva · M Petrou · R Sayeed · G Krasopoulos · R Lee · J Digby · S Reilly · C Bakogiannis · D Tousoulis · B Kessler · B Casadei · K M Channon · C Antoniades
Diabetes 12/2015; 64(6),2207-2219. DOI:10.2337/db14-1011
· 8.47 Impact Factor
Evaluation of the role of miR-31-dependent reduction in dystrophin and nNOS on atrial- fibrillation-induced electrical remodelling in man.S Reilly · X Liu · R Carnicer · T Rajakumar · R Sayeed · G Krasopoulos · S Verheule · T Fulga · U Schotten · B Casadei
The Lancet 02/2015; 385:S82. DOI:10.1016/S0140-6736(15)60397-X
· 45.22 Impact Factor
Increased Nadph-Oxidase Activity Is Associated With Reduced Telomere Length in the Human Vascular Wall: The Influence of Oxidative Stress on Biological Aging.M Margaritis · S Patel · AS Antonopoulos · L Herdman · F Sanna · K Ananthan · M Petrou · G Krasopoulos · K M Channon · C Antoniades
Arteriosclerosis, Thrombosis, and Vascular Biology 2015; 35 (Suppl 1), A655-A655
· 6.0 Impact Factor
P106 * Loss of myocardial nNOS in human atrial fibrillation (AF) shortens action potential duration (APD) by increasing Ito: Implications for AF-induced electrical remodelling.X Liu · S Reilly · R Carnicer · A Recalde · G Krasopoulos · R Sayeed · R Desilva · B Casadei
Cardiovascular Research 07/2014; 103(suppl 1):S18. DOI:10.1093/cvr/cvu082.47
· 5.81 Impact Factor
A MiR-31-dependent Loss of Dystrophin & Nnos in the Human Atria Plays a Key Role in Atrial Fibrillation-induced Electrical Remodelling.S Reilly · X Liu · R Carnicer · T Rajakumar · R Sayeed · G Krasopoulos · S Verheule · T Fulga · U Schotten · B Casadei
Circulation 2014; 130 (Suppl 2), A17767-A17767
· 14.43 Impact Factor
Perivascular adipose tissue around the left internal mammary artery regulates oxidative stress in this graft through PI3k/Akt-mediated down-regulation of p22phox subunit of NADPH-oxidase.M Margaritis · A Antonopoulos · P Coutinho · R Sayeed · R De Silva · M Petrou · G Krasopoulos · R Lee · K M Channon · C Antoniades.
European Heart Journal 2014 vol. 35, pp. 1200-1201.
· 15.203 Impact Factor
Myocardial redox state as a regulator of PPAR-gamma signalling in epicardial adipose tissue of patients with ischemic heart disease: insights from the Oxford CABG Bioresource.A Antonopoulos · M Margaritis · P Coutinho · C Psarros · D Tousoulis · G Krasopoulos · M Petrou · B Casadei · K M Channon · C Antoniades.
European Heart Journal 2014 vol. 35, pp. 446-446.
· 15.203 Impact Factor
Reply to actis dato et Al. (I). G Krasopoulos · P Goldstraw
European journal of cardio-thoracic surgery 03/2012; 41(3):725. DOI:10.1093/ejcts/ezr088
· 2.81 Impact Factor
The effect of prehospital time related variables on mortality following severe thoracic trauma. E Kidher · G Krasopoulos · T Coats · A Charitou · P Magee · R Uppal · T Athanasiou
Injury 05/2011; 43(9):1386-92. DOI:10.1016/j.injury.2011.04.014
· 2.46 Impact Factor
Minimally invasive repair of pectus excavatum deformity G Krasopoulos · P GoldstrawEuropean journal of cardio-thoracic surgery 02/2011; 39(2):149-58. DOI:10.1016/j.ejcts.2010.07.019
· 2.81 Impact Factor
Editorial: Eur. J. Cardiothorac. Surg. 2011; 39(2): 159 – 159 by F. Robicsek
Economic analysis of esophageal stenting for management of malignant dysphagia C Rao · A Haycock · E Zacharakis · G Krasopoulos · D Yakoub · A Protopapas · A Darzi · G B Hanna · T Athanasiou
Diseases of the Esophagus 02/2009; 22(4):337-47. DOI:10.1111/j.1442-2050.2008.00916.x
· 2.06 Impact Factor
Aspirin “resistance” and risk of cardiovascular morbidity: Systematic review and meta-analysis
G Krasopoulos · S J Brister · W S Beattie · M R Buchanan.
BMJ 02/2008; 336(7637):195-8. DOI:10.1136/bmj.39430.529549.BE
· 16.38 Impact Factor
Editorial: BMJ, 2008 336: 166-167 by G. Biondi-Zoccai & M. Lotrionte
Media: – TV News & Newspapers: CNN, CTV, Ch-4, Daily Telegraph, Washington Post
Web Pages: National Institute of Health Research – DARE (NHS), The Heart, British Heart Foundation, British Carciovascular Society, MedPage Today, Irish Med. News, Englemed News
Custom-tailored valved conduit for complex aortic root disease
G Krasopoulos · T E David · S Armstrong
The Journal of thoracic and cardiovascular surgery 02/2008; 135(1):3-7 / DOI:10.1016/j.jtcvs.2007.06.016
· 3.99 Impact Factor
Selected article by CTSNet – Jan 2014
Invited commentary – Self and parental assessment after minimally invasive repair of pectus excavatum: Lasting satisfaction after bar removal
P Goldstraw · G Krasopoulos
The Annals of thoracic surgery 06/2007; 83(5):1849. DOI:10.1016/j.athoracsur.2007.02.038
· 3.65 Impact Factor
Nuss procedure improves the quality of life in young mate adults with pectus excavatum deformity
G Krasopoulos · M Dusmet · G Ladas · P Goldstraw
European Journal of Cardio-Thoracic Surgery 02/2006; 29(1):1-5 / DOI:10.1016/j.ejcts.2005.09.018
· 2.81 Impact Factor
Clampless Arterial Coronary Artery Bypass Grafting with the Use of Magnetic Coupling Devices.
T Athanasiou · H Ashrafian · H Asrafian · G Krasopoulos · S Purkayastha · V Malinowski · S Al-Ruzzeh · B Glenville · R De La Stanbridge · R Casula
Journal of Cardiac Surgery 01/2006; 21(1):69-74; discussion 75-6. DOI:10.1111/j.1540-8191.2006.00172.x
· 0.89 Impact Factor
Emergency thoracotomy in the pre-hospital setting: a procedure requiring clarification.
T Athanasiou · G Krasopoulos · P Nambiar · T Coats · M Petrou · P Magee · R Uppal
European Journal of DOI:10.1016/j.ejcts.2004.03.016
· 2.81 Impact Factor
Sclerosing mediastinitis with aortic valve regurgitation and aortic root dilatation.
G St Krasopoulos · M Ibrahim · G Venn
Journal of the Royal Society of Medicine 03/2000; 93(2):83.
· 2.02 Impact Factor
Left Atrial Appendage Occlusion with the Amplatzer AmuletTM for Stroke Prevention in Atrial Fibrillation: The First Case in Greece.
A Tzikas · L Karagounis · M Bouktsi · A Drevelegas · D Parcharidou · S Ioannidis · G Krasopoulos · G Giannakoulas
Hell J Cardiol 2013 Sep-Oct;54(5):408-412.
· 1.227 Impact Factor
Greek guidelines for the use of antiplatelet agents on primary and secondary prevention of cardiovascular diseases.
I Goudevenos, G Krasopoulos, A Tselepis et al
Hell J Cardiol 2013 Feb. 2013.
· 1.227 Impact Factor
Oesophageal leiomyoma, a rare tumour. Presentation of two cases.
M Douzinas, G Krasopoulos, G Lazopoulos, N Haroulis.
Hell J CardiolActa Chirur. Hell. 1996, Vol. 6 (Suppl.): 16
Book Chapters
Cases in Adult Congenital Heart Disease – Surgical repair of Ebstein’s anomaly.
G. Krasopoulos, P. Catarino, H. Uemura
Publisher: Elsevier, Prof. M. Gatzoulis
Hospital Surgery – Thoracic Trauma.
G. Krasopoulos, S. S. Panesar, T. Athanasiou
Publisher: Cambridge University Press, Prof. A. Darzi
EDUCATION & TRAINING
FRCS-CTh – Intercollegiate Cardiothoracic Specialty Examination (Royal College of Surgeons of England, 2005)
MRCS – Surgical Board Examination (Royal College of Surgeons of England, 1998)
PhD (University of Athens, 1999)
MD (Athems Medical School, 1993)