The Impact of Severe Anastomotic Leak on Long-term Survival and Cancer Recurrence After Surgical Resection for Esophageal Malignancy [1]
A French multicenter database was used to assess the relationship between severe anastomotic leak on outcomes after esophagectomy. Among 2439 pts, 8.5% developed a severe leak. This was associated with lower median overall survival (36 mos vs 55 mos) and disease-free survival (34 mos vs 48 mos), a 28% increased likelihood of death, and a significant increase in recurrence.