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Preoperative Sildenafil administration in children undergoing cardiac surgery: a randomized controlled preconditioning study [1]

Submitted by ctsnetstaff [2] on Fri, 2016-05-06 10:11

The effectivity of Sildenafil for preoperative preconditioning in pediatric heart surgery was tested in a randomized trial. Thirteen children each with low-dose (0.06 mg/kg), high-dose (0.6 mg/kg) or no preconditioning underwent VSD closure. Sildenafil application did not alter myocardial injury, cardiac function, inotropic needs or postoperative course.

Source name: 
Eur J Cardiothorac Surg
Resource link: 
http://ejcts.oxfordjournals.org/content/49/5/1403.abstract [3]
Subspecialty(ies): 
Cardiac [4]
Author(s): 
Varsha Walavalkar, Egmond Evers, Suresh Pujar, Kiran Viralam, Shreesha Maiya, Stefan Frerich, Colin John, Shekhar Rao, Chinnaswamy Reddy, Bart Spronck, Frits W. Prinzen, Tammo Delhaas, and Ward Y. Vanagt
Source URL:https://www.ctsnet.org/jans/preoperative-sildenafil-administration-children-undergoing-cardiac-surgery-randomized

Links
[1] https://www.ctsnet.org/jans/preoperative-sildenafil-administration-children-undergoing-cardiac-surgery-randomized [2] https://www.ctsnet.org/home/ctsnetstaff [3] http://ejcts.oxfordjournals.org/content/49/5/1403.abstract [4] https://www.ctsnet.org/categories/cardiac