Revisiting Aortic Valve Prosthesis Choice in Patients Less Than 50 Years Old: AUTHEARTVISIT 10-Year Results [1]
This population-based cohort study examined midterm outcomes of surgical aortic valve replacement with mechanical or bioprosthetic valves in patients less than 50 years old. A total of 991 patients were included. Multivariable Cox regression showed no significant difference in overall survival, with a median follow up period of 6.2 years. However, reoperation-free survival was significantly decreased and risk of reoperation was increased in those who received bioprosthetic valves. Although a difference in overall survival was not apparent in this study, the lower rate of reoperation with mechanical valves might have an impact on long-term survival.