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Journal and News Scan

Source: Journal of the National Cancer Institute
Author(s): Mark A. Healy, Huiying Yin, Rishindra M. Reddy and Sandra L. Wong

Routine use of PET scans to follow up asymptomatic patients do not affect survival, according to this retrospective analysis of a cohort of 97,152 lung cancer and 4,446 esophageal cancer patients. They compared high and low level of use of PET centers, and found no differences in two-year survival. 

Source: JAMA
Author(s): Manu Shankar-Hari; Gary S. Phillips; Mitchell L. Levy; Christopher W. Seymour; Vincent X. Liu; Clifford S. Deutschman; Derek C. Angus; Gordon D. Rubenfeld; Mervyn Singer; for the Sepsis Definitions Task Force

This consensus effort provides a new definition for septic shock, which affects a subset of patients with sepsis.   The definition requires the presence of circulatory disturbances (BP unresponsive to fluids and requiring pressors), cellular and metabolic abnormalities (serum lactate level >2 mmol/L).  The presence of these criteria is associated with an increased risk of mortality compared to sepsis alone.

Source: Journal of Thoracic and Cardiovascular Surgery
Author(s): Dark JH

A succinct editorial from a British academic transplant surgeon. It discusses the need for stratifying the utilization of donor lungs based on recent and previous retrospective papers from North American and European databases. Professor Dark also briefly debates the needs for research on assessing and optimizing the organs.

Source: Circulation Research
Author(s): Libby P, Bornfeldt KE, Tall AR

An Editorial suggesting that atheroma is here to stay...

Source: BMJ
Author(s): Ruijun Chen, Nihar R Desai, Joseph S Ross, Weiwei Zhang, Katherine H Chau, Brian Wayda, Karthik Murugiah, Daniel Y Lu, Amit Mittal, Harlan M Krumholz, Harold H Hines Jr

The authors studied the rate of publication of completed clinical trials performed in academic medical centers in the US.  Among over 4,300 such trials, only 36% were published within 2 years of completion, and only 66% were ultimately published at any time.  There was considerable variation in publication rates among institutions.

Source: JAMA Surgery
Author(s): Robert H. Hollis; Brandon A. Singletary; James T. McMurtrie; Laura A. Graham; Joshua S. Richman; Carla N. Holcomb; Kamal M. Itani; Thomas M. Maddox; Mary T. Hawn

The authors studied the relationship of outcomes after non-cardiac surgery to blood transfusion among over 7,300 patients.   Patients with significant bleeding were excluded.  Patients were stratified according to the occurence of postoperative MI and the nadir hematocrit value (20-24%, 24-27%, 27-30%).  The outcome was 30-day mortality.   In the no-transfusion group, mortality increased as nadir hematocrit decreased.  In patients with an MI, mortality was lower in the low hematocrit patients who received a transfusion.  In patients without an MI, mortality was increased for patients in the high hematocrit group who received a transfusion.  In patients with stable cardiovascular status postoperatively, a restrictive transfusion policy is appropriate.  Those who have cardiovascular instability or MI may require a different transfusion strategy.

Source: JAMA Surgery
Author(s): Sherif Y. Shalaby; Trenton R. Foster; Michael R. Hall; Kirstyn E. Brownson; Penny Vasilas; Daniel G. Federman; Hamid R. Mojibian; Alan Dardik

The authors studied outcomes after endovascular AAA aneurysm repair (EVAR) to assess whether ongoing aortic remodeling related to systemic inflammatory disease (SID) contributes to an increased incidence of endoleak.  65% of 79 treated patients had systemic inflammatory disease.  Major complication rates were increased 7-fold in the group with SID.  This group also experienced a 2.5-fold greater incidence of endoleaks and a 2-fold greater rate of late sac expansion.  More interventions were required in the SID group.

Source: New England Journal of Medicine
Author(s): Kenneth Rosenfield, Jon S. Matsumura, Seemant Chaturvedi, Tom Riles, Gary M. Ansel, D. Chris Metzger, Lawrence Wechsler, Michael R. Jaff, and William Gray for the ACT I Investigators

Over 1400 patients with asymptomatic severe carotid stenosis were randomized to with carotid stenting or endarterectomy.  The endpoints were the composite of death, stroke, or acute MI within 30 days, or ipsilateral stroke.   Stenting was non-inferior to endarterectomy.   The rate of the composite endpoint was 3.8% vs 3.4% (stent vs surgery).  At 30 days to 5 years, freedom from ipsilateral stroke was 97.8% vs 97.3%.  Cumulative stroke-free survival rates were 93.1% and 94.7%.

Source: Change.org
Author(s): UK thoracic surgeons

NHS England is evaluating a series of operations in the UK. One of the procedures it is looking at is Pectus Excavatum surgery. 

At the moment the proposal is to ban all pectus surgery in the UK funded by the NHS. This document is currently available for 25 more days for public consultation and to obtain the views of the public and profession widely. 

There are only around 200 of these operations conducted per year in the UK and therefore we believe that the money saved will be minimal. 

However the benefit to patients of Pectus surgery, many patients of which are teenagers or adolescents we believe is very large in terms of their confidence and ability to face the world. 

These patients are also often not able to afford the money to fund this operation as they are not yet earning. 

If you also believe in Pectus Excavatum as a good operation, and you would like us to help preserve this in the UK then please sign this signature and send this on to others. 

you are also able to send a personal view to NHS england as well as see all their documents here : 

https://www.engage.england.nhs.uk/consultation/clinical-commissioning-wa...

 

Many thanks for your Help 

 

The UK thoracic Surgery community 

 

 

Source: The Thoracic and Cardiovascular Surgeon
Author(s): Welter, Stefan; Cheufou, Danjouma; Zahin, Mahmood; Kampe, Sandra; Darwiche, Kaid; Weinreich, Gerhard; Stamatis, Georgios

This article analyzes the amount of lung function loss in 31 patients who underwent bilateral metastasectomy for pulmonary metastases. 

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