Twenty-Year Outcome after Mitral Repair Versus Replacement for Severe Degenerative Mitral Regurgitation. Analysis of a Large, Prospective, Multicenter International Registry

In this article, the authors describe their findings from a direct, propensity score matching and inverse probability-of-treatment weighting analysis of patients with degenerative MR with a flail leaflet, included in a multicenter registry which includes patients from 6 tertiary European and US centers. They compare outcomes between patients undergoing mitral valve repair (n=1709) and mitral valve replacement (213). They conclude that in this cohort of patients, MV repair is associated with lower operative mortality and better long-term survival than MV replacement.