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  1. Cardiac

Twenty-Year Outcome after Mitral Repair Versus Replacement for Severe Degenerative Mitral Regurgitation. Analysis of a Large, Prospective, Multicenter International Registry

  • December 6, 2016

Submitted by: J. Rafael Sadaba

Source: Circulation
Source URL: http://circ.ahajournals.org/content/early/2016/11/29/CIRCULATIONAHA.116.023340.1…

Keywords:

  • Cardiac
Author(s): Lazam S, Vanoverschelde JL, Tribouilloy C, Grigioni F, Suri RM, Avierinos JF, de Meester C, Barbieri A, Rusinaru D, Russo A, Pasquet AA, Michelena HI, Huebner M, Maalouf J, Clavel MA, Szymanski C, Enriquez-Sarano ME, and on behalf of the MIDA investigators

In this article, the authors describe their findings from a direct, propensity score matching and inverse probability-of-treatment weighting analysis of patients with degenerative MR with a flail leaflet, included in a multicenter registry which includes patients from 6 tertiary European and US centers. They compare outcomes between patients undergoing mitral valve repair (n=1709) and mitral valve replacement (213). They conclude that in this cohort of patients, MV repair is associated with lower operative mortality and better long-term survival than MV replacement.

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