Molecular Biology
An experiment that may find some translational value in the drive to elucidate inflammation as a target for controlling cardiovascular disease. Columbia University has on this occasion focused on elucidating by flow cytometry the nuances...
High tumor mutational burden (TMB) predicts not only response to immune checkpoint inhibitors (ICI) in advanced non-small cell lung cancer (NSCLC) but also immune-related toxicity. In this single-center cohort of...
An experiment that may find some translational value in the drive to elucidate inflammation as a target for controlling cardiovascular disease. Columbia University has on this occasion focused on elucidating...
This paper details an under-development animal model to study the vascular pathology of vein grafts in a variation of the initial Carrel canine bypass experiment. The possible findings on detrimental...
The clinical problem addressed in this study is bleeding in patients who undergo ECMO. The authors endeavor to address the issue through a quantitative cohort study by reflecting on how...
A review that may affect pharma strategy in the immediate future.
...Autopsy examination of lungs from patients who died from SARS-CoV-2 infection, with comparison to the morphologic & molecular features of lungs from patients who died from ARDS secondary to influenza...
a readable review that advances the position that Adolphe Quetelet’s formula is now clinically obsolete
...Interesting hypothesis in a rodent model of myxomatous degeneration.
...Interesting metanalytic review on the effect of binary gender in mammals.
...Another refreshing change of pace with an interesting pre-translational contibution to the genetics of atrial dysrhythmias.
...Interesting to follow up the translational potential of this rodent-model of carotid intimal re-hyperplasia/stenosis.
...A very easy-to-read editorial that digests a manuscript on the IMPROVE study. The study suggests an association of this group of enzymes to the Matrix Metalloproteinases and hence a theory...

