PCSK6-Mediated Regulation of Vascular Remodeling

A very easy-to-read editorial that digests a manuscript on the IMPROVE study. The study suggests an association of this group of enzymes to the Matrix Metalloproteinases and hence a theory on explaining the biochemistry of atheromatous plaque in relation to smooth muscle cells: if this will be translated to humans, it may offer a route of novel pharmacologic intervention to cardiovascular disease.