This consensus effort provides a new definition for septic shock, which affects a subset of patients with sepsis. The definition requires the presence of circulatory disturbances (BP unresponsive to fluids and requiring pressors), cellular and metabolic abnormalities (serum lactate level >2 mmol/L). The presence of these criteria is associated with an increased risk of mortality compared to sepsis alone.
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Developing a New Definition and Assessing New Clinical Criteria for Septic Shock
Submitted by: Mark Ferguson
Source: JAMA
Keywords:
Author(s): Manu Shankar-Hari; Gary S. Phillips; Mitchell L. Levy; Christopher W. Seymour; Vincent X. Liu; Clifford S. Deutschman; Derek C. Angus; Gordon D. Rubenfeld; Mervyn Singer; for the Sepsis Definitions Task Force
