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Long-Term Outcomes of Chordal Replacement With Expanded Polytetrafluoroethylene Sutures to Repair Mitral Leaflet Prolapse

Submitted by: Saurabh Gupta

Source: The Journal of Thoracic and Cardiovascular Surgery

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Author(s): Tirone E. David, MD; Carolyn M. David, BN; Myriam Lafreniere-Roula, PhD; Cedric Manlhiot, PhD

David et al. examined the durability of mitral repair using using chordal replacement with expanded polytetrafluoroethylene sutures to correct leaflet prolapse.They evaluated 186 patients who underwent isolated chordal replacement, and 560 patients who underwent both leaflet resection and choral replacement.

The authors demonstrated that re-do cardiac surgery and isolated anterior leaflet prolapse resulted in an increased hazard of mitral valve reoperation. The probability of recurrent moderate or severe mitral regurgitation using repeated measures regression models was 14.1% at 20 years. Variables associated with recurrent MR in multivariable regression analysis were left ventricular ejection

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