A reexamination of data from the National Lung Screening Trial (NLST) with nodules above the 4mm, has been shown that increasing the nodule size threshold for a positive screen, substantially reduces the false-positive CT screenings rate and increase slightly the lung cancer missed or delayed but without affecting the survival.
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Projected Outcomes Using Different Nodule Sizes to Define a Positive CT Lung Cancer Screening Examination
Submitted by: Marcelo Jimenez
Source: Journal of the National Cancer Institute
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Author(s): David S. Gierada, Paul Pinsky, Hrudaya Nath, Caroline Chiles, Fenghai Duan and Denise R. Aberle
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