Thus far, only 3 randomized controlled trials (RCTs) have compared stereotactive ablative radiotherapy (SABR) versus surgery in patients with early stage NSCLC (STARS trial, ROSEL trial, and ACOSOG Z4099 trial). Unfortunately all 3 were unable to meet the accrual goals and were closed early. The current study is a pooled analysis of patients in the STARS trial and ROSEL trial (n=31 in SABR group and n=27 in surgery group). All patients had clinical stage I NSCLC (
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Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomized controlled trials – Part 1 of 9
Submitted by: Lisa Brown
Source: The Lancet Oncology
Source URL: http://www.ncbi.nlm.nih.gov/pubmed/25981812
Keywords:
Author(s): Joe Y Chang, Suresh Senan, Marinus A Paul, Reza J Mehran, Alexander V Louie, Peter Balter, Harry J M Groen, Stephen E McRae, Joachim Widder, Lei Feng, Ben E E M van den Borne, Mark F Munsell, Coen Hurkmans, Donald A Berry, Erik van Werkoven, John J Kresl, Anne-Marie Dingemans, Omar Dawood, Cornelius J A Haasbeek, Larry S Carpenter, Katrien De Jaeger, Ritsuko Komaki, Ben J Slotman, Egbert F Smit, Jack A Roth

1 Comment
Very interested findings that if repeated by other investigators then it will have serious impact on the management of early stage lung cancer