In this promising investigation, authors have found changes associated with airway cancerization in large airways in lung cancer patients, while these changes are absent in cancer-free smokers. And in addition, with shorter distance from tumors, airway cancerization expression increases statistically.
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Transcriptomic Architecture of the Adjacent Airway Field Cancerization in Non–Small Cell Lung Cancer
Submitted by: Marcelo Jimenez
Source: Journal of The National Cancer Institute
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Author(s): Humam Kadara, Junya Fujimoto, Suk-Young Yoo, Yuho Maki, Adam C. Gower, Mohamed Kabbout, Melinda M. Garcia, Chi-Wan Chow, Zuoming Chu, Gabriella Mendoza, Li Shen, Neda Kalhor, Waun Ki Hong, Cesar Moran, Jing Wang, Avrum Spira, Kevin R. Coombes and Ignacio I. Wistuba
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