Impact of Preoperative Chronic Kidney Disease in 2,531 High-Risk and Inoperable Patients Undergoing Transcatheter Aortic Valve Replacement in the PARTNER Trial [1]
This analysis of PARTNER data evaluated the impact of chronic kidney disease (CKD) on outcomes after TAVR. Patients were grouped according to GFR as none/mild, moderate, and severe renal disease. Severe disease was most common among women with diabetes. Severe disease was associated with a 50% increase in 30-day mortality and 1-year cominbed mortality and all-cause rehospitalization. Assessment of renal function may help risk stratify patients who are candidates for TAVR.