Real-World Outcomes of Lobectomy, Segmentectomy and Wedge Resection for the Treatment of Stage C-IA Lung Carcinoma

This retrospective study compared outcomes for 90-day mortality and five-year overall survival estimates in patients who underwent lobectomy, segmentectomy, or wedge resection for stage c-IA lung carcinoma between 2016-2022. Of the 19,453 patients, 72.2 percent underwent lobectomy, 21.5 percent underwent segmentectomy and 6.3 percent underwent wedge resection. The multivariable proportional hazards regression analysis found that wedge resection was associated with worse overall survival compared to lobectomy, with no significant difference between lobectomy and segmentectomy. The authors’ analysis of contemporary real-world patients with clinical stage IA lung carcinoma supports lobectomy as the reference treatment in daily practice for those able to undergo surgery.