An interesting case series of cardiotoxicity of modern chemotherapy attempting to elucidate mechanisms of heart failure. This pilot study could well lead to further investigation of finite pathways related to surgical aspects of transplanation, anti-rejection therapy in particular: The authors propose that the immune system is a mediator of cardiac dusfunction.
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Baseline Immunoglobulin E Levels as a Marker of Doxorubicin- and Trastuzumab-Associated Cardiac Dysfunction
Submitted by: Aristotle Protopapas
Source: Circulation Research
Keywords:
Author(s): Beer LA, Kossenkov AV, Liu Q, Luning Prak E, Domchek S, Speicher DW, Ky B
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