Beneficial Effect of Left Atrial Appendage Closure During Cardiac Surgery: A Meta-Analysis of 280,585 Patients

This meta-analysis looks at the impact on concomitant LAA closure during cardiac surgery in patients with AF prior to surgery. The authors analyzed 22 studies with over 250,000 patients. Overall, LAA closure reduced the incidence of postoperative stroke and mortality. Therefore, the authors conclude that LAA closure should be performed in any cardiac surgery in patients with preoperative AF.