Plasma metabolomic profiles were examined to determine differences in social determinants of health between Black and white women. This observational study paves the groundwork for further investigation of social disparity in atheromatous disease. The historical hereditary effect of renin aldosterone axis regulation may be proven to reflect such disparities (related to slave trade and water deprivation) concerning people with African heritage. In fact, the study concluded that the significant difference in metabolomic profiles between Black and white women may be associated with coronary heart disease risk and racial disparities in the US.
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Differences in Metabolomic Profiles Between Black and White Women and Risk of Coronary Heart Disease: an Observational Study of Women From Four US Cohorts
Submitted by: Aristotle Protopapas
Source: Circulation Research
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Author(s): Hu J, Yao J, Deng S, Balasubramanian R, Jiménez MC, Li J, Guo X, Cruz DE, Gao Y, Huang T, Zeleznik OA, Ngo D, Liu S, Rosal MC, Nassir R, Paynter NP, Albert CM, Tracy RP, Durda P, Liu Y, Taylor KD, Johnson WC, Sun Q, Rimm EB, Eliassen AH, Rich SS, Rotter JI, Gerszten RE, Clish CB, Rexrode KM.
